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ACTH 4-11(Adrenocorticotropic Hormone(4-11),human)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
ACTH 4-11(Adrenocorticotropic Hormone(4-11),human)图片
CAS NO:67224-41-3
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
ACTH 4-11 (Adrenocorticotropic Hormone (4-11), human) 是一种促肾上腺皮质激素片段，仅在高剂量（100 和 1000 nM）下具有弱 α-促黑素细胞激素 (α-MSH) 效力。
Cas No.67224-41-3
别名Adrenocorticotropic Hormone (4-11), human
Canonical SMILESMet-Glu-His-Phe-Arg-Trp-Gly-Lys
分子式C50H71N15O11S
分子量1090.26
溶解度DMF: 10mg/mL,DMSO: 10mg/mL,PBS (pH 7.2): 10mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ACTH (4-11), an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM).

α-melanocyte stimulating hormone (MSH) induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. Adrenocorticotropic hormone (ACTH) possesses the same amino acid sequence as MSH does. α-MSH induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. ACTH (4-11) loses almost all activity for the binding to melanocortin receptor 1 (MC1R)[1].

[1]. Hirobe T, et al. ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. J Exp Zool. 2000 May 1;286(6):632-40.