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KCC2 blocker 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KCC2 blocker 1图片
CAS NO:1228439-36-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议

产品介绍
KCC2 blocker 1 是一种口服有效的,选择性的 K+-Cl- 共转运蛋白 KCC2 阻滞剂,IC50 为 1 μM。KCC2 blocker 1 是一种脯氨酸苄酯,具有抗癫痫作用。
Cas No.1228439-36-8
Canonical SMILESO=C(OCC1=CC=CC=C1)C2(CC3=CC=C(S(=O)(C)=O)C=C3)N(C(C)=O)CCC2
分子式C22H25NO5S
分子量415.5
溶解度DMSO: 250 mg/mL (601.68 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

KCC2 blocker 1 is an orally active and selective K+-Cl- cotransporter KCC2 blocker with an IC50 of 1 μM. KCC2 blocker 1 is a benzyl prolinate and has antiepileptic effect[1].

[1]. PÉgurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5.