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Bevantolol hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bevantolol hydrochloride图片
CAS NO:42864-78-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
25mg电议
50mg电议
100mg电议

产品介绍
Bevantolol hydrochloride 是一种选择性的 β1/α1-肾上腺素受体 (β1/α1-adrenergic receptor) 拮抗剂,在大鼠大脑皮层中的 pKi 值分别为 7.83、6.9。Bevantolol hydrochloride 是有效的 Ca2+ 拮抗剂。
Cas No.42864-78-8
别名贝凡洛尔盐酸盐
Canonical SMILESOC(CNCCC1=CC=C(C(OC)=C1)OC)COC2=CC=CC(C)=C2.[H]Cl
分子式C20H28ClNO4
分子量381.89
溶解度DMSO: 62.5 mg/mL (163.66 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist[1][2].

[1]. M Takita, et al. Selectivity of Bevantolol Hydrochloride Towards Alpha- And Beta-Adrenoceptor Subtypes in Rat Cerebral Cortex. Jpn J Pharmacol. 1992 Feb;58(2):193-6. [2]. Takahiro Horinouchi, et al. Different Changes of Plasma Membrane Beta-Adrenoceptors in Rat Heart After Chronic Administration of Propranolol, Atenolol and Bevantolol. Life Sci. 2007 Jul 12;81(5):399-404.