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Rabeprazole Sulfide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Rabeprazole Sulfide图片
CAS NO:117977-21-6
包装:100mg
市场价:495元

产品介绍
Rabeprazole Sulfide 是 Rabeprazole 的活性代谢产物。Rabeprazole 是一种 质子泵 (proton pump) 抑制剂，可通过与胃壁细胞中的 (H+/K+)-ATPase 相互作用来抑制胃酸分泌。Rabeprazole 显着抑制幽门螺旋杆菌的活性。Rabeprazole 可用于各种消化系统疾病的研究。
Cas No.117977-21-6
别名2-[[[4-(3-甲氧基丙氧基)-3-甲基吡啶-2-基]甲基]硫代]-1H-苯并咪唑
Canonical SMILESCC1=C(OCCCOC)C=CN=C1CSC2=NC3=CC=CC=C3N2
分子式C18H21N3O2S
分子量343.44
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment[1][2].

[1]. Uno T, et al. Determination of rabeprazole and its active metabolite, rabeprazole thioether in human plasma by column-switching high-performance liquid chromatography and its application to pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 25;824(1-2):238-43. [2]. Tsutsui N, et al. A novel action of the proton pump inhibitor rabeprazole and its thioether derivative against the motility of Helicobacter pylori. Antimicrob Agents Chemother. 2000 Nov;44(11):3069-73.