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AM 12
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AM 12图片
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Canonical SMILESOC1=CC(O)=C2C(OC(C3=C(Br)C=CC=C3)=C(C2=O)O)=C1
分子式C15H9BrO5
分子量349.14
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TRPC5 inhibitor (IC50 = 0.28 μM); Galangin derivative. Exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Inhibits effects of TRPC5 activator (-)-Englerin A, but potentiates effects of physiological activators Sphingosine-1-phosphate and LPC.

Naylor et al (2016) Natural and synthetic flavonoid modulation of TRPC5 channels. Br.J.Pharmacol. 173 562 PMID:26565375