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m-PEG3-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
m-PEG3-Boc图片
CAS NO:1778219-81-0
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
m-PEG3-Boc 是一种 PROTAC linker,属于 PEG 和 Alkyl/ether 类,可用于合成 PROTAC。
Cas No.1778219-81-0
分子式C12H24O5
分子量248.32
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

m-PEG3-Boc is aPEG- andAlkyl/ether-basedPROTAC linkercan be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.