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m-PEG9-NHS ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
m-PEG9-NHS ester图片
CAS NO:1316189-13-5
包装:1g
市场价:6008元

产品介绍
m-PEG9-NHS ester 是一种基于 PEG 的 PROTAC linker,用于 PROTAC 合成。
Cas No.1316189-13-5
分子式C24H43NO13
分子量553.6
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

m-PEG9-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Alexander Chucholowski, et al. Cyclodextrin conjugates. WO2010017328A2.
[2]. Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.