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FATP1-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FATP1-IN-2图片
CAS NO:2650944-83-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
FATP1-IN-2 作为芳基哌嗪的衍生物,是一种具有口服活性的脂肪酸转运蛋白1 (FATP1) 抑制剂 (对人和小鼠的 IC50 值分别为 0.43 μM 和 0.39 μM)。
Cas No.2650944-83-3
分子式C19H20FN5O
分子量353.39
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM)[1].

FATP1-IN-2 (10 mg/kg; p.o.) shows a Cmax value above the mouse IC50 value[1].FATP1-IN-2 (3, 10, 30 mg/kg; p.o.; 4 weeks) shows TG content of each tissue does not change at any dose[1].

[1]. Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23(9):2560-2565.