CAS NO: | 2650944-83-3 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 2650944-83-3 |
分子式 | C19H20FN5O |
分子量 | 353.39 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM)[1]. FATP1-IN-2 (10 mg/kg; p.o.) shows a Cmax value above the mouse IC50 value[1].FATP1-IN-2 (3, 10, 30 mg/kg; p.o.; 4 weeks) shows TG content of each tissue does not change at any dose[1]. [1]. Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23(9):2560-2565. |