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Isoflupredone Acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isoflupredone Acetate图片
CAS NO:338-98-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Isoflupredone acetate 是一种具有抗炎活性的皮质类固醇。Isoflupredone acetate 可用于研究牛、马、猪等动物的酮症、肌肉骨骼疾病、过敏、感染、炎症等疾病。
Cas No.338-98-7
别名醋酸异氟泼尼松
分子式C23H29FO6
分子量420.47
溶解度DMSO : 125 mg/mL (297.29 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isoflupredone acetate is a corticosteroids with anti-inflammatory activity. Isoflupredone acetate can be used for research ketosis, musculoskeletal disorders, hypersensitivity, infections, inflammatory diseases in cows, horse, pigs, et al.[1][2].

Isoflupredone acetate (10-4, 10-7, or 10-10M; 48 or 96 h)mitigates the inflammatory and catabolic effects of IL-1β in synovial and osteochondral explants (from equine cadavers) to a greater extent in low concentrations (10-7M and 10-10M) than the high concentration (10-4M)[1].

Isoflupredone acetate (0.05 mg/kg; i.m.; on days 2 and 4 after the challenge) prevents dry-matter intake and average daily gain reductions, and leads to fasterMannheimia haemolytica-infected clinical improvement when co-treated withOxytetracycline[2].

Animal Model:96 weanling heifers (Bronchopneumonia was induced by intrabronchial infusion ofMannheimia haemolytica)[2]
Dosage:0.05 mg/kg
Administration:i.m.; on days 2 and 4 after the challenge
Result:Infection caused a reduction in dry-matter intake and average daily gain (ADG) in heifers.Prevented these reductions and resulted in faster clinical improvement when co-treated withOxytetracycline.

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