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Toralactone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Toralactone图片
CAS NO:41743-74-2
包装:1mg
市场价:1170元

产品介绍
Toralactone可从Cassiaobtusifolia中分离得到,通过Nrf2依赖的抗氧化机制介导肝保护。
Cas No.41743-74-2
别名决明内酯
Canonical SMILESO=C1C2=C(O)C3=C(O)C=C(OC)C=C3C=C2C=C(C)O1
分子式C15H12O5
分子量272.25
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1].

Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[2].

[1]. YongtaekSeo, et al. Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Research International. Volume 97, July 2017, Pages 340-346. [2]. Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC.