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Dapaconazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dapaconazole图片
CAS NO:1269726-67-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Dapaconazole 作为一种抗真菌化合物,抑制 sterol 14α-demethylase cytochrome P450 活性的 IC50 值为 1.4 μM。
Cas No.1269726-67-1
别名1-[2-(2,4-二氯苯基)-2-[[4-(三氟甲基)苯基]甲氧基]乙基]-1H-咪唑
分子式C19H15Cl2F3N2O
分子量415.24
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1].

Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 ± 0.3 μM[1].

Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 %[1].

[1]. Juliana SP, et al. Pharmacokinetics of Dapaconazole, A Novel Antifungal Agent, in Beagle Dogs and Inhibition of Cytochrome P450 Family 51. J Eur Acad Dermatol Venereol. 2018 Jun 10.