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5,7-Dimethoxyflavone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5,7-Dimethoxyflavone图片
CAS NO:21392-57-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
25mg电议
50mg电议

产品介绍
5,7-Dimethoxyflavone是Kaempferiaparviflora的主要成分之一,具有抗肥胖,抗炎和抗肿瘤作用。5,7-Dimethoxyflavone抑制细胞色素P450(CYP)3As。5,7-Dimethoxyflavone也是有效的抗乳腺癌蛋白(BCRP)抑制剂。
Cas No.21392-57-4
别名柯因二甲醚
Canonical SMILESO=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=CC(OC)=C13
分子式C17H14O4
分子量282.29
溶解度DMSO: 100 mg/mL (354.25 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].

[1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34.