| CAS NO: | 2250025-88-6 |
| 包装: | 5mg |
| 市场价: | 3150元 |
| Cas No. | 2250025-88-6 |
| Canonical SMILES | O=C1C(CCC(N1)=O)N2C(C3=C(C2=O)C=CC=C3NCC(NCCOCCOCCN4CCN(CC4)C5=CC=C(C=C5)NC6=NC(NC7=C(C=CC=C7)S(=O)(C(C)C)=O)=C(C=N6)Cl)=O)=O |
| 分子式 | C44H51ClN10O9S |
| 分子量 | 931.46 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | 4°C, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PROTAC® comprised of a highly promiscuous kinase inhibitor conjugated to the cereblon E3 ubiquitin ligase ligand, pomalidomide . Degrades a range of kinases in MOLT-4 and MOLM-14 cell lines. Negative control TL 13-27 is also available. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license. Huang et al (2018) A chemoproteomic approach to query the degradable kinome using a multi-kinase degrader. Cell Chem.Biol. 25 88 PMID:29129717 |
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