包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Canonical SMILES | O=C1C2=C([C@](CC)(O)C(OC2)=O)C=C3C4=NC5=CC=CC=C5C(CCNC(C)C)=C4CN31.OP(O)(O)=O |
分子式 | C25H27N3O4.H3PO4 |
分子量 | 531.49 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Topoisomerase I inhibitor. Forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. Inhibits growth of a range of cancer cell lines in vitro, as well as of ovarian and leukemia tumors in vivo. Kim et al (2015) Anticancer effects of CKD-602 (Camtobell®) via G2/M phase arrest in oral squamous cell carcinoma cell lines. Oncol.Lett. 9 136 PMID:25435947 |Jung et al (2006) The synergism between Belotecan and cisp. in gastric cancer. Cancer Res.Treat. 38 159 PMID:19771277 |