CAS NO: | 482646-13-9 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 482646-13-9 |
Canonical SMILES | O=C(N)CSC1=NN=C(COC2=CC=CC=C2C)N1C3=CC=CC=C3 |
分子式 | C18H18N4O2S |
分子量 | 354.43 |
溶解度 | DMSO : 250 mg/mL (705.36 mM) |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | A2ti-2 is a selective and low-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 230 µM[1]. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-2 prevents human papillomavirus type 16 (HPV16) infection[2]. A2ti-2 (compound 7a) is an annexin A2-S100A10 protein-protein interaction blocker[1]. A2ti-2 is less effective with<50% reduction in HPV16 PsV infection achieved at 100 µM. A2ti-1 decreases HPV16 entry with a 20% reduction at 100 µM[2]. References: |