CAS NO: | 157542-47-7 |
包装 | 价格(元) |
100μg | 电议 |
500μg | 电议 |
1mg | 电议 |
Cas No. | 157542-47-7 |
别名 | D-MYO-肌醇1,4,5,6-四(磷酸二氢酯)四钠盐,Ins(1,4,5,6)-P4 |
化学名 | D-myo-inositol-1,4,5,6-tetra(hydrogen phosphate), tetrasodium salt |
Canonical SMILES | O[C@@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@@H]1OP([O-])(O)=O.[Na+].[Na+].[Na+].[Na+] |
分子式 | C6H12O18P4•4Na |
分子量 | 588 |
溶解度 | 50mg/mL in water |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | D-myo-Inositol-1,4,5,6-tetrahosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.[1] D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella. Ins(1,4,5,6)-P4 antagonizes epidermal growth factor (EGF) signalling through the phosphatidylinositol 3-kinase pathway. Ins(1,4,5,6)-P4 (tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.[2] Reference: |