Chk2 Inhibitor (compound 1) 是一种有效的、选择性的检查点激酶 2 (Chk2) 抑制剂,对 Chk2 和 Chk1 的 IC50 分别为 13.5 nM 和 220.4 nM。 Chk2 Inhibitor 可引起强烈的共济失调毛细血管扩张症突变 (ATM) 依赖性 Chk2 介导的辐射防护作用。
Cas No. | 724708-21-8 |
Canonical SMILES | O=C(NCC/1)C2=C(C(C=CC=C3)=C3N2)C1=C4NC(N)=NC/4=O |
分子式 | C15H13N5O2 |
分子量 | 295.3 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | |