SMER 3 是一种雷帕霉素增强剂，是一种选择性 Skp1-Cullin-F-box (SCF)Met30 泛素连接酶抑制剂。 SMER 3 通过抑制 SCFMet30 增强雷帕霉素的生长抑制作用。
| Cas No. | 67200-34-4 |
| 化学名 | 9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one |
| Canonical SMILES | O=C1C2=CC=CC=C2C3=NC4=NON=C4N=C31 |
| 分子式 | C11H4N4O2 |
| 分子量 | 224.18 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 5 mg/ml,DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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