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Ec2la
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ec2la图片
CAS NO:2244579-87-9
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Ec2la 是一种口服活性大麻素 2 型受体 (CB2Rs) 正变构调节剂。
Cas No.2244579-87-9
Canonical SMILESCC1=C(C(N(C=C1Br)CC2=CC=C(C=C2)F)=O)NC(C3CCCCCC3)=O
分子式C21H24BrFN2O2
分子量435.33
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CB2 receptor positive allosteric modulator. Enhances CP 55940 and 2-Arachidonylglycerol -stimulated binding of [35S]GTPγS to CB2 receptors, but has no effect in the absence of agonist. Exhibits antinociceptive effects in an animal model of neuropathic pain.

Gado et al (2019) Identification of the first synthetic allosteric modulator of the CB2 receptors and evidence of its efficacy for neuropathic pain relief. J.Med.Chem. 62 276 PMID:29990428