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KI-7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KI-7图片
CAS NO:1489263-00-4
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
KI-7 是一种 A2B 腺苷受体正变构调节剂。
Cas No.1489263-00-4
Canonical SMILESO=C(C(C1=CN(C2=CC=CC=C12)CC3=CC=CC=C3)=O)NC4=CC=CC=C4
分子式C23H18N2O2
分子量354.4
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Adenosine A2B receptor positive allosteric modulator. Potentiates the NECA -induced increase in cAMP production in CHO cells expressing A2B receptors. Also potentiates the effects of NECA and the A2B receptor agonist BAY 60-6583 in mediating osteoblast differentiation from MSCs in vitro.

Trincavelli et al (2014) Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. Biochim.Biophys.Acta 1843 2957 PMID:25241343 |Trincavelli et al (2014) Allosteric modulators of human A2B adenosine receptor. Biochim.Biophys.Acta 1840 1194 PMID:24361612