CAS NO: | 1489263-00-4 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 1489263-00-4 |
Canonical SMILES | O=C(C(C1=CN(C2=CC=CC=C12)CC3=CC=CC=C3)=O)NC4=CC=CC=C4 |
分子式 | C23H18N2O2 |
分子量 | 354.4 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Adenosine A2B receptor positive allosteric modulator. Potentiates the NECA -induced increase in cAMP production in CHO cells expressing A2B receptors. Also potentiates the effects of NECA and the A2B receptor agonist BAY 60-6583 in mediating osteoblast differentiation from MSCs in vitro. Trincavelli et al (2014) Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. Biochim.Biophys.Acta 1843 2957 PMID:25241343 |Trincavelli et al (2014) Allosteric modulators of human A2B adenosine receptor. Biochim.Biophys.Acta 1840 1194 PMID:24361612 |