DREADD agonist 21 dihydrochloride 是一种有效的人毒蕈碱乙酰胆碱 M3 受体 (hM3Dq) 激动剂 (EC50=1.7 nM)。
Canonical SMILES | C1(N2CCNCC2)=NC(C=CC=C3)=C3NC4=C1C=CC=C4.Cl.Cl |
分子式 | C17H18N4.2HCl |
分子量 | 351.27 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Water soluble version of DREADD agonist 21 . Potent muscarinic DREADD agonist. Chen et al (2015) The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem.Neurosci. 18 476 PMID:25587888 |