CAS NO: | 1942-71-8 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 1942-71-8 |
别名 | 2-(4-叔丁基苯氧基)环己醇 |
化学名 | 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol |
Canonical SMILES | CC(C)(C1=CC=C(C=C1)OC2CCCCC2O)C |
分子式 | C16H24O2 |
分子量 | 248.36 |
溶解度 | 24.84mg/ml in DMSO, 24.84mg/ml in Ethanol |
储存条件 | Store at 4℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R. Schubert et al (2017) Identification and characterization of the first selective Y4 receptor positive allosteric modulator. J.Med.Chem. 60 7605 PMID:28795803 |