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tBPC
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
tBPC图片
CAS NO:1942-71-8
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Positive allosteric modulator of NPY Y4 receptor
Cas No.1942-71-8
别名2-(4-叔丁基苯氧基)环己醇
化学名2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol
Canonical SMILESCC(C)(C1=CC=C(C=C1)OC2CCCCC2O)C
分子式C16H24O2
分子量248.36
溶解度24.84mg/ml in DMSO, 24.84mg/ml in Ethanol
储存条件Store at 4℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R.

Schubert et al (2017) Identification and characterization of the first selective Y4 receptor positive allosteric modulator. J.Med.Chem. 60 7605 PMID:28795803