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PF 04628935
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF 04628935图片
CAS NO:1383719-97-8
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
Cas No.1383719-97-8
Canonical SMILESClC1=C(CN2CC3(CCN(C(CC4=CN(C=C(C)S5)C5=N4)=O)CC3)C2)C=CC(N6N=CC=N6)=C1
分子式C24H26ClN7OS
分子量496.03
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Potent ghrelin receptor inverse agonist (IC50 = 4.6 nM). Orally bioavailable and exhibits reasonable brain penetration.

Kung et al (2012) Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor. Bioorg.Med.Chem.Lett. 22 5410 PMID:22677316