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SAR 216471 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SAR 216471 hydrochloride图片
CAS NO:1279829-64-9
包装:10mg
市场价:3587元

产品介绍
Potent P2Y12 antagonist; orally available
Cas No.1279829-64-9
Canonical SMILESClC1=CC=C2C(C(C(NC3=CC=C(N4C(C)=C(C(CCC)=O)C=N4)N=N3)=O)=CN2CC(N5CCN(C)CC5)=O)=C1.Cl
分子式C28H31ClN8O3.HCl
分子量599.51
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Potent P2Y12 antagonist (IC50 = 17 nM). Displays antiplatelet and antithrombotic activity in vivo. Orally available.

Boldron et al (2014) N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J.Med.Chem. 57 7293 PMID:25075638