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TC NTR1 17
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TC NTR1 17图片
CAS NO:1146757-96-1
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Selective NTS1 partial agonist
Cas No.1146757-96-1
Canonical SMILESO=C(N[C@@H](CC(C)C)C(O)=O)C2=NN(C(C3=C(OC)C=CC=C3OC)=C2)C1=C(C=CC(Cl)=C4)C4=NC=C1
分子式C27H27ClN4O5
分子量522.98
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Non-peptide neurotensin receptor 1 (NTS1) partial agonist (EC50 <15.6 nM and Emax = 63% of neurotensin response in Ca2+ mobilization assay). Exhibits over 50-fold selectivity for NTS1 over NTS2 and GPR35.

Hershberger et al (2014) Imidazole-derived agonists for the neurotensin 1 receptor. Bioorg.Med.Chem.Lett. 24 262 PMID:24332089