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LY 341495 disodium salt
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
LY 341495 disodium salt图片
包装与价格：
包装价格(元)
1mg电议
10mg电议
50mg电议

产品介绍
Potent and selective group II mGlu antagonist; disodium salt of LY 341495
Canonical SMILES[Na+].[Na+].[H][C@@]1(C[C@@H]1C([O-])=O)[C@@](N)(CC1C2=CC=CC=C2OC2=C1C=CC=C2)C([O-])=O
分子式C20H17NNa2O5
分子量397.33
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Highly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495

Fitzjohn et al (1998) The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacology 37 1445 PMID:9886667 |Ornstein et al (1998) 2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl) glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioav J.Med.Chem. 41 358 PMID:9464367 |Johnson et al (1999) [3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells. Neuropharmacology 38 1519 PMID:10530814