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(R)-UT-155
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(R)-UT-155图片
CAS NO:2031161-54-1
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
(R)-UT-155(compound11)是一种选择性的、雄激素受体降解物(SARD)配体。活性低于S型异构体。
Cas No.2031161-54-1
Canonical SMILESO=C([C@](C)(O)CN1C(C=CC(F)=C2)=C2C=C1)NC3=CC=C(C#N)C(C(F)(F)F)=C3
分子式C20H15F4N3O2
分子量405.35
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer[1][2].

[1]. US20180360805. [2]. Ponnusamy S, et al. Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer. Cancer Res. 2017 Nov 15;77(22):6282-6298.