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Bevenopran(CB-5945)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bevenopran(CB-5945)图片
CAS NO:676500-67-7
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Bevenopran (CB-5945) 是一种外周 μ-阿片受体拮抗剂。
Cas No.676500-67-7
别名CB-5945; ADL-5945
Canonical SMILESO=C(C1=NC=C(OC2=CC=C(CNCCC3CCOCC3)C=C2OC)N=C1)N
分子式C20H26N4O4
分子量386.44
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bevenopran is a peripheral μ-opioid receptor antagonist.

Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].

[1]. Diego L, et al. Novel opioid antagonists for opioid-induced bowel dysfunction. Expert Opin Investig Drugs. 2011 Aug;20(8):1047-56. [2]. Siemens W, et al. Advances in pharmacotherapy for opioid-induced constipation - a systematic review. Expert Opin Pharmacother. 2015 Mar;16(4):515-32.