CAS NO: | 1351373-47-1 |
包装: | 1g |
市场价: | 9700元 |
Cas No. | 1351373-47-1 |
分子式 | C24H42O10 |
分子量 | 490.58 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Bis-propargyl-PEG9 is aPEG-basedPROTAC linkerused in the synthesis of PROTACs. Bis-propargyl-PEG9 can be used to synthesize the bivalent estrogen receptor ligands[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Shan M, et al. Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding. Chembiochem. 2011 Nov 25;12(17):2587-98. |