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Benzyl-PEG3-CH2-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Benzyl-PEG3-CH2-Boc图片
CAS NO:1443467-88-6
包装:1g
市场价:8914元

产品介绍
Benzyl-PEG3-CH2-Boc 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。
Cas No.1443467-88-6
分子式C19H30O6
分子量354.44
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Benzyl-PEG3-CH2-Boc is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Girardini M, et al. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479.