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Boc-aminooxy-PEG1-propargyl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Boc-aminooxy-PEG1-propargyl图片
CAS NO:1895922-72-1
包装:1g
市场价:13250元

产品介绍
Boc-aminooxy-PEG1-propargyl 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No.1895922-72-1
分子式C10H17NO4
分子量215.25
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.