CAS NO: | 147317-15-5 |
包装 | 价格(元) |
500μg | 电议 |
1mg | 电议 |
5mg | 电议 |
Cas No. | 147317-15-5 |
Canonical SMILES | CC1CC(C)C2C(C=CC(C3(C)C(C)O3)C2/C(O)=C4C(N(C)C(C(C)CC)C\4=O)=O)C1 |
分子式 | C26H39NO4 |
分子量 | 429.6 |
溶解度 | DMSO: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also inhibits the migration of murine neutrophils when used at concentrations of 10 and 20 μM. References |