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GSK3326595(EPZ015938)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK3326595(EPZ015938)图片
CAS NO:1616392-22-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议

产品介绍
GSK3326595 (EPZ015938) (EPZ015938) 是一种有效的、选择性的、可逆的蛋白质精氨酸甲基转移酶 5 (PRMT5) 抑制剂,IC50 为 6.2 nM。
Cas No.1616392-22-3
别名EPZ015938
Canonical SMILESO=C(C)N1CCC(NC2=NC=NC(C(NC[C@H](O)CN3CCC(C=CC=C4)=C4C3)=O)=C2)CC1
分子式C24H32N6O3
分子量452.55
溶解度DMSO : ≥ 30 mg/mL (66.29 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GSK3326595 is a potent, selective, reversible inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 6.2 nM.

GSK3326595 (EPZ015938), has entered clinical trials for the treatment of solid tumors and non-Hodgkin's lymphoma[1].

[1]. WO 2016022605 A1