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Taurocholic Acid-d4(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taurocholic Acid-d4(sodium salt)图片
CAS NO:2410279-93-3
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of taurocholic acid
Cas No.2410279-93-3
别名牛磺胆酸钠盐,N-Choloyltaurine-d4 sodium
Canonical SMILESC[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C([2H])([2H])[C@H](O)C([2H])([2H])C[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C.[Na+]
分子式C26H40D4NO7S.Na
分子量541.7
溶解度DMF: 25 mg/mL,DMSO: 20 mg/mL,Ethanol: 2 mg/mL,PBS (pH 7.2): 3 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Taurocholic acid-d4(TCA-d4) is intended for use as an internal standard for the quantification of TCA by GC- or LC-MS. TCA is a taurine-conjugated form of the primary bile acid cholic acid .1Serum levels of TCA are decreased in patients with Crohn's disease and those with ulcerative colitis with no extraintestinal manifestations, but are increased in patients with ulcerative colitis accompanied by hepatobiliary disease.2

1.Lefebvre, P., Cariou, B., Lien, F., et al.Role of bile acids and bile acid receptors in metabolic regulationPhysiol. Rev.89(1)147-191(2009) 2.Gnewuch, C., Liebisch, G., Langmann, T., et al.Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel diseaseWorld J. Gastroenterol.15(25)3134-3141(2009)