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Massarigenin C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Massarigenin C图片
CAS NO:496926-08-0
包装:1mg
市场价:3251元

产品介绍
A fungal metabolite
Cas No.496926-08-0
Canonical SMILESO=C1C=C[C@@H](C)[C@@]2([C@@H](O)C(OC2=O)=C)[C@H]1O
分子式C11H12O5
分子量224.2
溶解度Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 µM).2It is also an inhibitor of yeast α-glucosidase (IC50= 1.25 mM).1It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.

1.Verastegui-OmaÑa, B., Rebollar-Ramos, D., PÉrez-VÁsquez, A., et al.α-Glucosidase inhibitors from Malbranchea flavoroseJ. Nat. Prod.80(1)190-195(2017) 2.Zhang, G.F., Han, W.B., Cui, J.T., et al.Neuraminidase inhibitory polyketides from the marine-derived fungus Phoma herbaruPlanta Med.78(1)76-78(2012)