您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Solanesol
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Solanesol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Solanesol图片
CAS NO:13190-97-1
包装与价格:
包装价格(元)
1 g电议
5 g电议
10 g电议
25 g电议

产品介绍
茄尼醇是一种脂肪族萜烯醇,主要存在于茄科植物中,具有抗炎、神经保护和抗菌活性。
Cas No.13190-97-1
别名茄尼醇
Canonical SMILESOC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C
分子式C45H74O
分子量631.1
溶解度Ethanol: 0.25mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Solanesol is a trisesquiterpenoid that has been found inN. tabacumand has diverse biological activities.1,2,3It is active againstE. coli,M. phlei,P. aeruginosa, andS. aureus.1Solanesol (40 µM) increases basal heme oxygenase-1 (HO-1) and nuclear factor erythroid 2-related factor 2 (Nrf2) activities and inhibits LPS-induced production of IL-6, IL-1β, and TNF-α in RAW 264.7 cells.2It reduces escape latency in the Morris water maze and the number of slips in a beam-crossing task in a rat model of Huntington's disease induced by 3-nitropropionic acid when administered at doses of 5, 10, and 15 mg/kg.3Solanesol is also a precursor in the formation of polynuclear aromatic hydrocarbons (PAHs), which are carcinogenic components of tobacco smoke, and has been used as a synthetic intermediate in the synthesis of coenzyme Q10and vitamin K analogs that have antioxidant activities.1

1.Yan, N., Liu, Y., Liu, L., et al.Bioactivities and medicinal value of solanesol and its accumulation, extraction technology, and determination methodsBiomolecules9(8)334(2019) 2.Yao, X., Lu, B., LÜ, C., et al.Solanesol induces the expression of heme oxygenase-1 via p38 and Akt and suppresses the production of proinflammatory cytokines in RAW264.7 cellsFood Funct.8(1)132-141(2017) 3.Mehan, S., Monga, V., Rani, M., et al.Neuroprotective effect of solanesol against 3-nitropropionic acid-induced Huntington's disease-like behavioral, biochemical, and cellular alterations: Restoration of coenzyme-Q10-mediated mitochondrial dysfunctionIndian J. Pharmacol.50(6)309-319(2018)