您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > DA-3003-2
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
DA-3003-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DA-3003-2图片
CAS NO:383907-47-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Cas No.383907-47-9
Canonical SMILESO=C(C(NCCN1CCOCC1)=C2Cl)C3=C(N=CC=C3)C2=O
分子式C15H16ClN3O3
分子量321.8
溶解度DMF: 30 mg/ml,DMSO: 20 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cdc25 dual-specific protein tyrosine phosphatases are important for cell cycle progression and often overexpressed in cancers. Through the removal of inhibitory phosphates, they function to catalyze the activation of cyclin-Cdk complexes. DA-3003-2 is a Cdc25 phosphatase inhibitor (IC50 = 0.82 µM for human recombinant Cdc25B) that demonstrates antiproliferative activity. At 20 µM, it has been shown to arrest asynchronous PC-3 prostate cancer cells in G2/M phase.