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Allethrin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Allethrin图片
CAS NO:584-79-2
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
Allethrin 是一种拟除虫菊酯类杀虫剂,是一种主要的驱蚊剂。 Allethrin 在大鼠睾丸癌细胞 (LC540) 中诱导氧化应激、细胞凋亡和钙释放。 Allethrin 诱导 BCL-2、caspase-3 活化和细胞内钙的释放。
Cas No.584-79-2
别名丙烯菊酯
Canonical SMILESC/C(C)=C/C1C(C)(C)C1C(OC2C(C)=C(CC=C)C(C2)=O)=O
分子式C19H26O3
分子量302.4
溶解度Chloroform: Slightly Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Allethrin is a pyrethroid insecticide and modulator of voltage-gated sodium channels (NaV). It delays channel deactivation in cockroach giant axons when used at a concentration of 1 μM. Allethrin is 100-fold more potent at insect than rat NaV1.8 channels expressed in Xenopus oocytes. It decreases egg production by and is lethal to mosquitoes (LC50 = 0.01%). Allethrin induces production of reactive oxygen species (ROS), lipid peroxidation, and apoptosis in rat primary Leydig cells. In vivo, the smoke of an allethrin-based mosquito coil increases levels of the hepatic enzymes ALT and AST and induces hepatocyte apoptosis as well as emphysema and lung hyperplasia in mice.