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Metyrapone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Metyrapone图片
CAS NO:54-36-4
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
50mg电议

产品介绍
Metyrapone (Su-4885) 是一种有效且具有口服活性的 11β-羟化酶抑制剂和自噬激活剂,还抑制醛固酮的产生。
Cas No.54-36-4
别名美替拉酮; Su-4885
化学名2-methyl-1,2-di(pyridin-3-yl)propan-1-one
Canonical SMILESO=C(C1=CC=CN=C1)C(C)(C)C2=CC=CN=C2
分子式C14H14N2O
分子量226.27
溶解度≥ 13.45mg/mL in Water
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Metyrapone is an inhibitor of cytochrome P450-mediated ω/ω-1 hydroxylase activity and CYP11B1.Target: CYP11B1Metyrapone is a drug used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism). Metyrapone blocks cortisol synthesis by reversibly inhibiting steroid 11β-hydroxylase. This stimulates ACTH secretion, which in turn increases plasma 11-Deoxycortisol levels.