Valproic acid (VPA) sodium (2:1) 是一种具有口服活性的 HDAC 抑制剂，IC50 在 0.5 和 2 mM 范围内，还抑制 HDAC1 (IC50, 400 μM)，并诱导 HDAC2 的蛋白酶体降解。
| Cas No. | 76584-70-8 |
| 别名 | 双丙戊酸钠,VPA (sodium) |
| 化学名 | sodium;2-propylpentanoate;2-propylpentanoic acid |
| Canonical SMILES | CCCC(CCC)C(=O)O.CCCC(CCC)C(=O)[O-].[Na+] |
| 分子式 | C8H16O2.C8H15O2.Na |
| 分子量 | 310.41 |
| 溶解度 | ≥ 14.2mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Divalproex sodium (USAN) consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.[1] Its chief use in medicine is as a treatment for bipolar disorder, epilepsy and in the prevention of migraines. |
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