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Salbutamol Sulfate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Salbutamol Sulfate图片
CAS NO:51022-70-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
250mg电议
500mg电议

产品介绍
沙丁胺醇半硫酸盐 (Albuterol hemisulfate) 是一种短效 β2 肾上腺素受体激动剂目标:β2 肾上腺素受体沙丁胺醇半硫酸盐 (Albuterol hemisulfate) 是一种短效、选择性的 β2 肾上腺素受体激动剂,用于治疗哮喘和 COPD。
Cas No.51022-70-9
别名沙丁胺醇半硫酸盐; Albuterol hemisulfate; AH-3365 hemisulfate
化学名4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;sulfuric acid
Canonical SMILESCC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.OS(=O)(=O)O
分子式C13H21NO3.H2SO4
分子量337.39
溶解度≥ 16.9mg/mL in Water
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Salbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting β2 adrenergic receptor agonistTarget: β2 Adrenergic ReceptorSalbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. All the effects of R,S-salbutamol on guinea-pig skeletal muscles are due to the activity of the R-enantiomer. Thus there is a common enantiomeric profile for the skeletal muscle and bronchorelaxant activity of the compound [1]. Short-term Salbutamol intake did appear to improve performance during intense submaximal exercise with concomitant increase in substrate availability and utilization, but the exact mechanisms involved need further investigation [2]. Short-term administration of salbutamol increases voluntary muscle strength in man. However, the magnitude and duration of this effect vary between muscle groups. This study implies that the beta 2-adrenoceptor agonists may be of therapeutic potential in altering skeletal muscle function in humans [3].

References:
[1]. Prior, C., M.B. Leonard, and J.R. McCullough, Effects of the enantiomers of R,S-salbutamol on incompletely fused tetanic contractions of slow- and fast-twitch skeletal muscles of the guinea-pig. Br J Pharmacol, 1998. 123(3): p. 558-64.
[2]. Collomp, K., et al., Effects of short-term oral salbutamol administration on exercise endurance and metabolism. J Appl Physiol (1985), 2000. 89(2): p. 430-6.
[3]. Martineau, L., et al., Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men. Clin Sci (Lond), 1992. 83(5): p. 615-21.