CAS NO: | 145108-58-3 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
50mg | 电议 |
Cas No. | 145108-58-3 |
别名 | 盐酸右美托咪定; (+)-Medetomidine hydrochloride; (S)-Medetomidine hydrochloride |
化学名 | 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole;hydrochloride |
Canonical SMILES | CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl |
分子式 | C13H16N2.HCl |
分子量 | 236.74 |
溶解度 | ≥ 11.837mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.Target: Adrenergic alpha-2 ReceptorDexmedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Dexmedetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Dexmedetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3]. References: |