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Taurine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taurine图片
CAS NO:107-35-7
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
50mg电议

产品介绍
牛磺酸是一种含硫氨基酸,是一种参与细胞体积调节的有机渗透物,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度中发挥作用。
Cas No.107-35-7
别名牛磺酸; 2-Aminoethanesulfonic acid
化学名2-aminoethanesulfonic acid
Canonical SMILESC(CS(=O)(=O)O)N
分子式C2H7NO3S
分子量125.15
溶解度25 mg/mL in Water(199.76 mM; Need ultrasonic)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Taurine is an organic acid widely distributed in animal tissues.Target: OthersTaurine is a major constituent of bile and can be found in the large intestine and accounts for approximately 0.1% of total human body weight [1]. Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms [2]. In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs [3]. Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function [4].

References:
[1]. Huxtable, R.J., Physiological actions of taurine. Physiol Rev, 1992. 72(1): p. 101-63.
[2]. Huxtable, R.J., Taurine in the central nervous system and the mammalian actions of taurine. Prog Neurobiol, 1989. 32(6): p. 471-533.
[3]. Chesney, R.W., Taurine: its biological role and clinical implications. Adv Pediatr, 1985. 32: p. 1-42.
[4]. Pion, P.D., et al., Myocardial failure in cats associated with low plasma taurine: a reversible cardiomyopathy. Science, 1987. 237(4816): p. 764-8.