CAS NO: | 896106-16-4 |
包装: | 100mg |
市场价: | 347元 |
Cas No. | 896106-16-4 |
别名 | 马来酸咪喹莫特; R 837 maleate |
化学名 | 1-isobutyl-1H-imidazo[4,5-c]quinolin-4(5H)-imine maleate |
Canonical SMILES | CC(CN1C=NC2=C1C3=CC=CC=C3NC2=N)C.O=C(O)/C([H])=C([H])\C(O)=O |
分子式 | C18H20N4O4 |
分子量 | 356.38 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist. In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1]. References: |