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Imiquimod hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Imiquimod hydrochloride图片
CAS NO:99011-78-6
包装:100mg
市场价:389元

产品介绍
Imiquimod hydrochloride (R 837 hydrochloride) 是一种免疫反应调节剂,是一种选择性 toll 样受体 7 (TLR7) 激动剂。
Cas No.99011-78-6
别名盐酸咪喹莫特; R 837 hydrochloride
化学名1-isobutyl-1H-imidazo[4,5-c]quinolin-4(5H)-imine hydrochloride
Canonical SMILESCC(CN1C=NC2=C1C3=CC=CC=C3NC2=N)C.Cl
分子式C14H17ClN4
分子量276.76
溶解度≥ 5.54mg/mL in DMSO with ultrasonic and warming
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7agonist.

In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].

References:
[1]. Bilu D, et al. Imiquimod: modes of action. Br J Dermatol. 2003 Nov;149 Suppl 66:5-8.