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RU 24969 hemisuccinate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RU 24969 hemisuccinate图片
CAS NO:66611-27-6
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
RU 24969 hemisuccinate 是一种优先的 5-HT1B 激动剂,Ki 为 0.38 nM,但对 5-HT1A 受体 (Ki=2.5 nM) 也显示出明显的亲和力,并且对大脑中的其他受体位点具有低亲和力。
Cas No.66611-27-6
别名5-甲氧基-3-(1,2,3,6-四氢-4-吡啶基)-1H-吲哚半琥珀酸盐
Canonical SMILESOC(=O)CCC(O)=O.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1
分子式C14H16N2O.½C4H6O4
分子量287.34
溶解度DMF: slightly soluble,DMSO: slightly soluble,Ethanol: slightly soluble,PBS (pH 7.2): 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412 PMID:8450834 |Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129 PMID:10837852 |Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties. Eur.J.Med.Chem. 22 33