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Nemifitide diTFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nemifitide diTFA图片
CAS NO:204992-09-6
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议

产品介绍
Nemifitide diTFA (INN 00835 diTFA) 是一种合成的五肽抗抑郁药,具有迅速起效的潜力。Nemifitide diTFA 是黑色素细胞抑制因子 (MIF) 的肽类似物。Nemifitide diTFA 可以透过血脑屏障。
Cas No.204992-09-6
别名INN 00835 diTFA
分子式C37H45F7N10O10
分子量922.8
溶解度Water: 250 mg/mL (270.91 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action[1]. Nemifitide diTFA is a peptide analog of melanocyte-inhibiting factor (MIF)[2]. Nemifitide diTFA can cross the blood-brain barrier[3].

[1]. Kelly JP, et al. The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients. J Affect Disord. 1999 Oct;55(2-3):231-5. [2]. Overstreet DH, et al. Antidepressant-like effects of a novel pentapeptide, nemifitide, in an animal model of depression. Psychopharmacology (Berl). 2004 Sep;175(3):303-9. [3]. Montgomery SA, et al. Efficacy and safety of 30 mg/d and 45 mg/d nemifitide compared to placebo in major depressivedisorder. Int J Neuropsychopharmacol. 2006 Oct;9(5):517-28.