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Nebracetam hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nebracetam hydrochloride图片
CAS NO:1177279-49-0
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Nebracetam hydrochloride 是 M1 毒蕈碱的激动剂,会引起胞内 Ca2+ 浓度升高。其 EC50 值为1.59 mM。
Cas No.1177279-49-0
别名WEB 1881 FU hydrochloride
Canonical SMILESO=C1N(CC2=CC=CC=C2)CC(CN)C1.[H]Cl
分子式C12H17ClN2O
分子量240.73
溶解度Soluble in DMSO
储存条件Store at -20℃, protect from light, sealed storage, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1].

Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms[2]. Animal Model: Male Wistar rats weighing 200-250 g[2].

[1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80. [2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26.