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Arotinolol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Arotinolol图片
CAS NO:68377-92-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Arotinolol 是一种非选择性的 α/β-肾上腺素受体 (α/β-adrenergic receptor ) 阻滞剂和一种血管扩张性 β-受体阻滞剂。Arotinolol 是一种抗高血压试剂,可用于治疗各种心血管疾病以及非心血管疾病。
Cas No.68377-92-4
别名阿罗洛尔
Canonical SMILESO=C(C1=CC=C(C2=CSC(SCC(O)CNC(C)(C)C)=N2)S1)N
分子式C15H21N3O2S3
分子量371.54
溶解度DMSO: 250 mg/mL (672.88 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases[1].

Arotinolol (oral gavage; 200 mg/kg; 8 weeks) can significantly decrease central arterial pressure (CAP) and pulse wave velocity (PWV), in addition, it reduces aortic collagen depositions and finally improves arterial stiffness in SHR mouse[1]. Animal Model: SHR mice[1]

[1]. Zhou W, et al. Mechanisms of improved aortic stiffness by arotinolol in spontaneously hypertensive rats.PLoS One. 2014 Feb 12;9(2):e88722.