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Osanetant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Osanetant图片
CAS NO:160492-56-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
Osanetant (SR142801) 是一种选择性的 NK3 受体拮抗剂。Osanetant 有抗焦虑和抗抑郁的作用,并被研究用于治疗精神分裂症。
Cas No.160492-56-8
别名奥沙奈坦,SR142801
Canonical SMILESO=C(N1C[C@@](CCCN2CCC(N(C(C)=O)C)(C3=CC=CC=C3)CC2)(C4=CC=C(Cl)C(Cl)=C4)CCC1)C5=CC=CC=C5
分子式C35H41Cl2N3O2
分子量606.62
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for the treatment of schizophrenia[1].

Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time[1]. Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time[1]. Animal Model: Male Mongolian gerbils of 7 weeks old (50-60 g)[1]

[1]. SalomÉ N, et al. Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. Pharmacol Biochem Behav. 2006 Apr;83(4):533-9.